Jacopo Ferruzzi

Assistant Professor

jacopo.ferruzzi@utdallas.edu
Phone: 972-883-4628
Office: UTSW EA 2.200D

800 West Campbell Rd.
Mailstop: BSB11
Richardson, TX 75080-3021

Education

BS & MS, Biomedical Engineering, University of Pisa, Italy

PhD, Biomedical Engineering, Yale University

Post-Doc, Biomedical Engineering, Boston University

Overview

Dr. Jacopo Ferruzzi is an Assistant Professor of Bioengineering at UT Dallas and the Principal Investigator of the Tissue Mechanics & Remodeling (TMR) Laboratory. His research expertise lies in the areas of biomechanics and mechanobiology. The ultimate goal of his work is to improve fundamental understanding of diseases associated with – and driven by – abnormal tissue mechanics, such as cardiovascular disease and cancer. Dr. Ferruzzi worked extensively in the area of cardiovascular biomechanics between the University of Pisa, Texas A&M University, and Yale University. He studied the progression of arterial stiffening and developed methods for “biomechanical phenotyping” arterial sections in vivo and ex vivo. By using experimental and computational methods, he investigated vascular conditions such as arterial aging, chronic hypertension, abdominal aortic aneurysms, and thoracic aortic dissections. While at Boston University, Dr. Ferruzzi explored the role of biomechanics in breast cancer by employing 3D cell culture techniques and label-free imaging methods. He investigated the mechanisms underlying collagen remodeling upon tumor growth and the mechanics of collective cancer invasion. His research program at UT Dallas employs a multidisciplinary and multiscale approach to dissect the relationship between altered mechanical properties, extracellular matrix organization, and cellular function.

Research Interests

Biomechanics, mechanobiology, experimental soft tissue mechanics, theoretical and computational modeling, tissue remodeling in cardiovascular disease and cancer