“Nanoelectronic Biosensors: Capability and Challenges”
Walter Hu, UT Dallas
There is an opportunity for dramatically increased synergy between electronics and biology. For example, electrical-based biosensors are emerging as powerful tools to quantify biochemical markers at low abundance, which is critical to many areas in the life sciences and health care, from disease diagnosis to drug discovery, environmental monitoring and bioterrorism. Compared to currently available optical- and mass-spectrum-based technologies, the power of electronic biosensors would be its low cost due to continuing exponential gains in functionality-per-unit-cost in nanoelectronics (Moore’s Law). In the next decade it may become possible for an IC chip to allow medical diagnoses without a clinic as well as instantaneous biological agent detection. To get there, however, a number of challenges have to be overcome given the complexity of bio and silicon interfaces. In this talk, recent progress of Si nanowire biosensors being developed in our group will be presented as one such example, and future challenges of the field will be discussed.
Dr. Hu’s research is focused on integrating nanoscale elements of electronics, chemistry and biology for emerging biomedical applications and renewable energy. He has extensive experience in the areas of electron beam lithography, nanoimprint lithography, innovative nanofabrication processes and metrology, polymer materials and surface chemistry. His group is making precision nanostructured materials, devices and systems using a combination of nanolithography and self assembly. The demonstrated single-digit lithography (resolution <10 nm) in his group has enabled high precision and control in engineering materials and devices. Dr. Hu has established collaborative partnerships with multiple groups across UT Dallas and at the University of Texas Southwestern Medical Center.